Human mesenchymal stem cells modulate allogeneic immune cell responses

Functions of natural killer cells

Functions of natural killer cells

Natural killer (NK) cells are effector lymphocytes of the innate immune system that management a number of varieties of tumors and microbial infections by limiting their unfold and subsequent tissue injury. Recent analysis highlights the truth that NK cells are additionally regulatory cells engaged in reciprocal interactions with dendritic cells, macrophages, T cells and endothelial …

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Human mesenchymal stem cells modulate allogeneic immune cell responses

Human mesenchymal stem cells modulate allogeneic immune cell responses

High-tidal-volume mechanical air flow utilized in sufferers with acute lung harm (ALI) can induce the discharge of inflammatory cytokines, as macrophage inflammatory protein-2 (MIP-2), recruitment of neutrophils, and disruption of alveolar epithelial and endothelial boundaries. Induced pluripotent stem cells (iPSCs) have been proven to enhance ALI in mice, however the mechanisms regulating the interactions between …

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