TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells.

TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells.

Cytotoxic lymphocytes, together with pure killer (NK) cells and T cells are distinguished by their capacity to eradicate goal cells by means of launch of secretory lysosomes. Conventional lysosomes and secretory lysosomes are a part of the pleomorphic endolysosomal system and characterised by its extremely dynamic nature. Several calcium-permeable TRP calcium channels play an important …

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