Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition

Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition

Microglia are resident macrophage-like APCs of the CNS. To stay away from escalation of inflammatory processes and bystander hurt contained in the CNS, microglia-driven inflammatory responses should be tightly regulated and every spatially and temporally restricted. Following traumatic, infectious, and autoimmune-mediated thoughts harm, NK cells have been found inside the CNS, but the helpful significance …

Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition Read More »