Antibodies, Assay Kits, cDNA, Cell-to-cell contact with hepatitis C virus-infected cells reduces functional capacity of natural killer cells, Chronic shift-lag alters the circadian clock of NK cells and promotes lung cancer growth in rats, Clia Kits, Culture Cells, Delineation and Modulation of the Natural Killer Cell Transcriptome in Rhesus Macaques During ZIKV and SIV Infections., Devices, DNA Templates, DNA Testing, Elisa Kits, Enzymes, Equipments, Functions of natural killer cells, Gels, General, Healthy Neonates Possess a CD56-Negative NK Cell Population with Reduced Anti-Viral Activity, Human mesenchymal stem cells modulate allogeneic immune cell responses, Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition, Isotypes, Medium & Serums, Overview of Strategies to Improve Therapy against Tumors Using Natural Killer Cell., Panel, Particles, Pcr Kits, Peptides, Reagents, Ria Kits, RNA, TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells., Vector & Virus

Antigens of Mycobacterium tuberculosis Stimulate CXCR6+ Natural Killer Cells

Natural killer (NK) cells take part in immunity in opposition to a number of pathogens by exerting cytotoxic and cytokine-production actions. Some NK cell subsets additionally mediate recall responses that resemble reminiscence of adaptive lymphocytes in opposition to antigenic and non-antigenic stimuli. The C-X-C motif chemokine receptor 6 (CXCR6) is essential for the event and upkeep of memory-like responses in murine NK cells. In people, a number of subsets of tissue-resident and circulating NK cells with totally different purposeful properties specific CXCR6. However, the function of CXCR6+ NK cells in immunity in opposition to related human pathogens is unknown. Here, we addressed whether or not murine and human CXCR6+ NK cells reply to antigens of Mycobacterium tuberculosis (Mtb). For this function, we evaluated the immunophenotype of hepatic and splenic CXCR6+ NK cells in mice uncovered to a cell-wall (CW) extract of Mtb pressure H37Rv. Also, we characterised the expression of CXCR6 in peripheral NK cells from energetic pulmonary tuberculosis (ATB) sufferers, people with latent TB an infection (LTBI), and wholesome volunteer donors (HD). Furthermore, we evaluated the responses of CXCR6+ NK cells from HD, LTBI, and ATB topics to the in vitro publicity to CW preparations of Mtb H37Rv and Mtb HN878.

Our outcomes confirmed that murine hepatic CXCR6+ NK cells broaden in vivo after consecutive administrations of Mtb H37Rv CW to mice. Remarkably, pooled hepatic and splenic, however not remoted splenic NK cells from handled mice, improve their cytokine manufacturing capability after an in vitro re-challenge with H37Rv CW. In people, CXCR6+ NK cells had been barely detected within the peripheral blood, though barely significative increments within the proportion of CXCR6+, CXCR6+CD49a-, CXCR6+CD49a+, and CXCR6+CD69+ NK cells had been noticed in ATB sufferers as in comparison with HD and LTBI people. In distinction, the growth of CXCR6+CD49a- and CXCR6+CD69+ NK cells in response to the in vitro stimulation with Mtb H37Rv was increased in LTBI people than in ATB sufferers. Finally, we discovered that Mtb HN878 CW generates IFN-γ-producing CXCR6+CD49a+ NK cells. Our outcomes exhibit that antigens of each laboratory-adapted and scientific Mtb strains are stimulating elements for murine and human CXCR6+ NK cells. Future research evaluating the function of CXCR6+ NK cells throughout TB are warranted.

Haploidentical transplantation in sufferers with a number of myeloma making use of pure killer cell alloreactive donors

Disease relapse is a vital downside after allogeneic stem cell transplantations in a number of myeloma (MM). To check the speculation that pure killer (NK) cell alloreactivity within the setting of a haploidentical stem cell transplantation (haploSCT) can cut back the chance of myeloma relapse, we carried out a small potential part 2 examine during which we transplanted poor-risk MM sufferers utilizing a killer cell immunoglobulin-like receptor (KIR)-ligand mismatched haploidentical donor. Patients obtained bone marrow grafts after reduced-intensity conditioning, with post-transplantation cyclophosphamide (PTCY) graft-versus-host-disease (GVHD) prophylaxis. The major endpoint was 1.5-year progression-free survival (PFS); stopping guidelines had been put in in case interim outcomes made a profit of 50% PFS at 1.5 years unlikely.

After inclusion of 12 sufferers, of which 9 had been evaluable for the first endpoint, all sufferers relapsed inside a median time of 90 days. All besides 1 affected person confirmed engraftment, with a median time to neutrophil restoration of 18 (12-30) days. The examine was prematurely terminated primarily based on the predefined stopping guidelines after the inclusion of 12 sufferers. With this small examine, we present that in chemo-resistant myeloma sufferers, NK cell KIR-mismatch just isn’t superior to traditional alloSCT. This technique, nevertheless, can function a platform for brand spanking new remedy ideas.Clinical Trial Registry

Irradiated Tumor Fibroblasts Avoid Immune Recognition and Retain Immunosuppressive Functions Over Natural Killer Cells

Primary Gastrointestinal Involvement in a Case of Extranodal-Extranasal Natural Killer T Cell Lymphoma

Extra-nasal varieties of Extra-nodal pure killer cell lymphoma (ENKL) have been identified with poorer prognoses than nasal kind with the worst responses to remedy. The present work introduces a case of ENKL with GI involvement with no nasal manifestations. We report a 56-year male farmer with fever, productive cough, dyspnea, anorexia, vomiting and chill along with malaise and cachexia of three months period referred to a hospital with acute stomach ache, and was identified as peritonitis because of perforated terminal ileum ulcer earlier than experiencing surgical procedure as a case of acute stomach. The pathologic examine of the related biopsy confirmed “ulceration and necrosis with dense fibrinoleukocytic exudation and granulation tissue formation. CT scan decided a bilateral mass like haziness which was extra more likely to be metastatic.

The evaluation of the earlier pathologic specimens raised Natural Killer/T cell Lymphoma (NKTL), the explanation for which we centered on the affected person’s sinuses and nasal space in addition to nasopharynx. There was no discovering in examination and endoscopy of sinuses. Pathology additionally discovered malignant excessive grade non-Hodgkin T cell lymphoma in specimens obtained from debridement of ulcer at terminal ileum. It additionally confirmed that almost all of the tumor cells had been optimistic for CD3, CD56, CD8, and LCA however damaging for CD19, CD20 and AE1/AE3.

Positive reactions for CD30 had been proven by some cells. CD56, CD3, and CD8 had been expressed by neoplastic cells and CD30 had been optimistic in few cells. Proliferative exercise (Ki67 index) was excessive (60-70%). This was the primary base to diagnose an extra-nodal extra-nasal NK/T cell lymphoma. In conclusion, Intestinal modifications at center age, particularly in males with nonspecific scientific manifestations is very suggested to be studied pathologically and genetically for T cell varieties like CD30 optimistic T cells that are normally engaged in ENKTL.

Antibodies, Assay Kits, cDNA, Cell-to-cell contact with hepatitis C virus-infected cells reduces functional capacity of natural killer cells, Chronic shift-lag alters the circadian clock of NK cells and promotes lung cancer growth in rats, Clia Kits, Culture Cells, Delineation and Modulation of the Natural Killer Cell Transcriptome in Rhesus Macaques During ZIKV and SIV Infections., Devices, DNA Templates, DNA Testing, Elisa Kits, Enzymes, Equipments, Functions of natural killer cells, Gels, General, Healthy Neonates Possess a CD56-Negative NK Cell Population with Reduced Anti-Viral Activity, Human mesenchymal stem cells modulate allogeneic immune cell responses, Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition, Isotypes, Medium & Serums, Overview of Strategies to Improve Therapy against Tumors Using Natural Killer Cell., Panel, Particles, Pcr Kits, Peptides, Reagents, Ria Kits, RNA, TRP Channels as Interior Designers: Remodeling the Endolysosomal Compartment in Natural Killer Cells., Vector & Virus

Irradiated Tumor Fibroblasts Avoid Immune Recognition and Retain Immunosuppressive Functions Over Natural Killer Cells

Recent research have demonstrated that radiotherapy is ready to induce anti-tumor immune responses along with mediating direct cytotoxic results. Cancer-associated fibroblasts (CAFs) are central constituents of the tumor stroma and take part actively in tumor immunoregulation. However, the capability of CAFs to affect immune responses within the context of radiotherapy continues to be poorly understood. This research was undertaken to find out whether or not ionizing radiation alters the CAF-mediated immunoregulatory results on pure killer (NK) cells. CAFs had been remoted from freshly resected non-small cell lung most cancers tissues, whereas NK cells had been ready from peripheral blood of wholesome donors.

Functional assays to review NK cell immune activation included proliferation charges, expression of cell floor markers, secretion of immunomodulators, cytotoxic assays, in addition to manufacturing of intracellular activation markers reminiscent of perforin and granzyme B. Our information present that CAFs inhibit NK cell activation by lowering their proliferation charges, the cytotoxic capability, the extent of degranulation, and the floor expression of stimulatory receptors, whereas concomitantly enhancing floor expression of inhibitory receptors.

Radiation delivered as single high-dose or in fractioned regimens didn’t reverse the immunosuppressive options exerted by CAFs over NK cells in vitro, regardless of triggering enhanced floor expression of a number of checkpoint ligands on irradiated CAFs. In abstract, CAFs mediate noticeable immune inhibitory results on cytokine-activated NK cells throughout co-culture in a donor-independent method. However, ionizing radiation doesn’t intervene with the CAF-mediated immunosuppressive results.

To study the cross-talk between NK cells and DCs in HCV an infection, we remoted monocytes and NK cells from 20 persistent HCV sufferers and 20 wholesome controls. Monocytes had been used to generate immature DCs which had been pulsed with HCV peptides (core, NS3-NS4 and NS5). Four totally different co-cultures had been carried out: E1: each DCs and NK cells had been from a persistent HCV affected person, E2: NK cells from a wholesome management co-cultured with DCs from a persistent HCV affected person, E3:

NK cells from a persistent HCV affected person co-cultured with DCs cells from a wholesome management and E4: each DCs and NK cells had been from a wholesome management. Using stream cytometry, we assessed the impact of those totally different co-cultures on ranges of maturation markers on DCs and ranges of activation/inhibition markers on NK cells. Results confirmed that peptide pulsed HCV DCs confirmed a maturation defect within the type of decreased HLA-DR, decreased CD86 and elevated CD83 expression particularly when co-cultured with HCV NK.

This was primarily as a result of core peptide pulsing and to a lesser extent as a result of NS5 pulsing whereas there was no impact with NS3-NS4 pulsing. Alternatively, HCV NK cells upregulated each activation and inhibition markers particularly when co-cultured with wholesome DCs. Compared to E2, E1 resulted in greater apoptosis of each NK cells and DCs with the proportion of NK apoptosis greater than that of DCs. Taken collectively, the information point out that HCV an infection impairs NK-DC cross-talk which can be a number one trigger in viral persistence and chronicity. This article is protected by copyright. All rights reserved.

Immune checkpoint molecules in pure killer cells as potential targets for most cancers immunotherapy

Recent research have demonstrated the potential of pure killer (NK) cells in immunotherapy to deal with a number of sorts of most cancers. NK cells are innate lymphoid cells that play important roles in tumor surveillance and management that effectively kill the tumor and don’t require the foremost histocompatibility complicated. The discovery of the NK’s potential as a promising therapeutic goal for most cancers is a reduction to oncologists as they face the problem of elevated chemo-resistant cancers. NK cells present nice potential towards stable and hematologic tumors and have progressively proven promise as a therapeutic goal for most cancers immunotherapy. The effector function of those cells is reliant on the steadiness of inhibitory and activating alerts.

Understanding the function of assorted immune checkpoint molecules within the exhaustion and impairment of NK cells when their inhibitory receptors are excessively expressed is especially necessary in most cancers immunotherapy research and scientific implementation. Emerging immune checkpoint receptors and molecules have been discovered to mediate NK cell dysfunction within the tumor microenvironment; this has introduced up the necessity to discover additional further NK cell-related immune checkpoints which may be exploited to reinforce the immune response to refractory cancers. Accordingly, this evaluate will give attention to the current findings in regards to the roles of immune checkpoint molecules and receptors within the regulation of NK cell operate, in addition to their potential software in tumor immunotherapy.

Irradiated Tumor Fibroblasts Avoid Immune Recognition and Retain Immunosuppressive Functions Over Natural Killer Cells

Natural Killer Cells in Immunotherapy: Are We Nearly There?

atural killer (NK) cells are potent anti-tumor and anti-microbial cells of our innate immune system. They are geared up with an unlimited array of receptors that acknowledge tumor cells and different pathogens. The innate immune exercise of NK cells develops sooner than the adaptive one carried out by T cells, and research counsel an necessary immunoregulatory function for every inhabitants towards the opposite.

The affiliation, noticed in acute myeloid leukemia sufferers receiving haploidentical killer-immunoglobulin-like-receptor-mismatched NK cells, with induction of full remission was the determinant to start an growing variety of scientific research administering NK cells for the therapy of most cancers sufferers. Unfortunately, though transfused NK cells demonstrated security, their noticed efficacy was poor.

Tapered Micro Tips

0-120-0007 3 mm
EUR 344

Tapered Micro Tips 5 mm Diameter Tapered Titanium Micro Tip

0-120-0008 5 mm
EUR 358

10 mm Diameter Solid Titanium Tip

0-120-0009 10 mm
EUR 504

13 mm Diameter Tapped Titanium Tip

0-120-0010 13 mm
EUR 595

13 mm Diameter Solid Titanium Tip

0-120-0011 13 mm
EUR 533

19 mm Diameter Tapped Titanium Tip

0-120-0012 19 mm
EUR 639

19 mm Diameter Solid Titanium Tip

0-120-0013 19 mm
EUR 570

25 mm Diameter Tapped Titanium Tip

0-120-0014 25 mm
EUR 682

25 mm Diameter Solid Titanium Tip

0-120-0015 25 mm
EUR 614

Flat Replaceable Tips 13 mm Diameter Flat Titanium Tip

0-120-0016 13 mm
EUR 86
Description: use with corresponding Tapped Tips and Tapped Extender Tips

Flat Replaceable Tips 19 mm Diameter Flat Titanium Tip

0-120-0017 19 mm
EUR 92
Description: use with corresponding Tapped Tips and Tapped Extender Tips

Flat Replaceable Tips 25 mm Diameter Flat Titanium Tip

0-120-0018 25 mm
EUR 100
Description: use with corresponding Tapped Tips and Tapped Extender Tips

Titanium Cup Tip, 250 ml

0-120-0019 250 ml
EUR 1377
Description: includes Interface Washers

Microtube Tray, 8 Position (for 250 ml Cup Tip)

0-120-0021 each
EUR 113
Description: includes Interface Washers

Continuous Flow Chamber

0-120-0026 each
EUR 774
Description: includes Interface Washers

Interface Washers 1.5” Diameter, 5/Pkg

0-120-003 1.5'' Diameter
EUR 31

13 mm Diameter Solid Titanium Extender Tip

0-120-0032 13 mm
EUR 301

13 mm Diameter Tapped Titanium Extender Tip

0-120-0033 13 mm
EUR 362

19 mm Diameter Solid Titanium Extender Tip

0-120-0034 19 mm
EUR 315

19 mm Diameter Tapped Titanium Extender Tip

0-120-0035 19 mm
EUR 375

25 mm Diameter Solid Titanium Extender Tip

0-120-0036 25 mm
EUR 328

25 mm Diameter Tapped Titanium Extender Tip

0-120-0037 25 mm
EUR 389

KoldPod, 1.5ml Micro Tube

0-120-0038 1.5 ml
EUR 152
Description: Thermo conductive tube pods

KoldPod, 15ml Conical Tube

0-120-0039 15 ml
EUR 275
Description: Thermo conductive tube pods

KoldPod, 50ml Conical Tube

0-120-0040 50 ml
EUR 290
Description: Thermo conductive tube pods

Model 150 V/T Ultrasonic Homogenizer

0-121-0002 210-240V/50-60Hz
EUR 2920
Description: Delivers up to 150 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample processing processing.

Model 300 V/T Ultrasonic Homogenizer

0-122-0002 210-240V/50-60Hz
EUR 3520
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample.

SONABOZ Sound Abating Chamber

0-125-0001 each
EUR 1020
Description: Reduces cavitational sound emitted during processing.

Model 3000 Ultrasonic Homogenizer

0-127-0002 210-240V/50-60Hz
EUR 4120
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip and includes an intergrated Sound Abating Chmaber to reduce cavitational sound emitted during processing. The Timer and Duty Cycle function increase preciosion in sample.

Model 3000MP Ultrasonic Homogenizer

0-128-0002 210-240V/50-60Hz
EUR 4720
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip with preciosion control from a microprocessor and a graphical user interface displayed on a large (145 mm) LCD display. The integrated Sound Abating Chamber reduces cavitational sound emitted during processing.

OMNICON® Zone Reader, 210-240V/50-60Hz

0-131-0002 210-240V/50-60Hz
EUR 35200
Description: Designed to Perform multi-plate Assays on round 90/100mm Petri Dishes. The integrated LED illumination system provides transmitted light for brightfield and darkfield illumination of transparent media.

OMNI-Noculator Peni Cylinder Filler, 210-240V/50-60Hz

0-134-0002 210-240V/50-60Hz
EUR 32200
Description: A robotic liquid handling system designed to dispense Peni Cylinders and fill Peni Cylinders with the corresponding antibiotic liquid sample.

Peni Cylinder Dispenser with Manual Hopper

0-144-0002 each
EUR 5406
Description: Dispenser can be configured to dispense 4 or 6 Peni Cylinders onto a petri dish.

Peni Cylinder Dispenser with Motorized Hopper, 100-240V/50-60Hz

0-144-0003 100-240V/50-60Hz
EUR 6254
Description: The motorized hopper can be configured to dispense 4 or 6 Peni Cylinders onto a petri Dispenser can be disassembled for disinfection.

Stainless Steel Peni Cylinder with Flat Face

0-144-0005 6mm I.D. x 8mm O.D. x 10mm Long
EUR 399
Description: sold in packages of 100 pieces

Stainless Steel Peni Cylinder with Chamfered Face

0-144-0006 6mm I.D. x 8mm O.D. x 10mm Long
EUR 412
Description: sold in packages of 100 pieces

Custom development of ELISAs for other species or antibody isotypes not listed in the catalog. Custom testing of samples for IgG/IgM/IgA or total (IgG+IgM+IgA)

000-CUS Custom
EUR 602

Alpha-Bungarotoxin, CF®405S, 500 ug

00002 1UG
EUR 527
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-bungarotoxin, CF405s

00002 500uG
EUR 594
Description: Minimum order quantity: 1 unit of 500uG

Alpha-Bungarotoxin, CF®405S, 500 ug

00002-1 EA
EUR 527

Alpha-Bungarotoxin, CF®405S 100ug

00002-100ug 100uG
EUR 132
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®680R, 500 ug

9-00003
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®680R, 500 ug

00003-1 EA
EUR 527

Alpha-Bungarotoxin, CF®680R 100ug

9-00003
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®640R, 500 ug

9-00004
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®640R, 500 ug

00004-1 EA
EUR 527

Alpha-Bungarotoxin, CF®640R 100ug

9-00004
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

9-00005
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

00005-1 EA
EUR 527

Alpha-Bungarotoxin CF®488A 100ug

9-00005
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

9-00006
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

00006-1 EA
EUR 527

Alpha-Bungarotoxin, CF®568 100ug

9-00006
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

9-00007
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

00007-1 EA
EUR 527

Alpha-Bungarotoxin CF®594 100ug

9-00007
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

9-00009
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

00009-1 EA
EUR 527

Alpha-Bungarotoxin, CF®633 100ug

9-00009
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, 1 mg

00010-1 1MG
EUR 193
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, 1 mg

00010-1-1 EA
EUR 193

Fluorescein-Alpha-Bungarotoxin, 500 ug

00011 500uG
EUR 376
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-Alpha-Bungarotoxin, 500 ug

00011-1 EA
EUR 376

Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

00012 500uG
EUR 394
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

00012-1 EA
EUR 394

Fluorescein-alpha-bungarotoxin, 10x50ug

00013 10ST
EUR 436
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-alpha-bungarotoxin, 10x50ug

00013-1 EA
EUR 436

Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

00014 10ST
EUR 494
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

00014-1 EA
EUR 494

Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

00015 500uG
EUR 494
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

00015-1 EA
EUR 494

Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

00016 10ST
EUR 560
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

00016-1 EA
EUR 560

Biotin-XX-A-Bungarotoxin, 500 ug

00017 500uG
EUR 455
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Biotin-XX-A-Bungarotoxin, 500 ug

00017-1 EA
EUR 455

Alpha-Bungarotoxin, CF®555, 500 ug

9-00018
  • Ask for price
  • Ask for price
  • 500uG
  • 100ug
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®555, 500 ug

00018-1 EA
EUR 527

Alpha-Bungarotoxin, CF®555 100ug

9-00018
  • Ask for price
  • Ask for price
  • 500uG
  • 100ug
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Acrylamide, Chemzymes Ultra Pure®

00019-100 100g
EUR 91
Description: 79-06-1

Acrylamide, Chemzymes Ultra Pure®

00019-500 500g
EUR 241
Description: 79-06-1

Biotin-cAMP, 1 mg

00020 1MG
EUR 298
Description: N/A

Biotin-cAMP, 1 mg

00020-1 20ST
EUR 298
Description: N/A

Biotin-cAMP, 50 ug

00020-1-1 EA
EUR 414

Biotin-cGMP, 1 mg

00021 1MG
EUR 331
Description: N/A

Biotin-cGMP, 1 mg

00021-1 20ST
EUR 331
Description: N/A

Biotin-cGMP, 20x50 ug

00021-1-1 EA
EUR 447

Cyanine 644-cAMP, 1 mg

00022 1MG
EUR 496
Description: N/A

Cyanine 644-cAMP, 1 mg

00022-1 20ST
EUR 496
Description: N/A

Cyanine 644-cAMP, 20x50 ug

00022-1-1 EA
EUR 647

Fluorescein Methotrexate, Triammonium Salt, 1 mg

00023 1MG
EUR 285
Description: N/A

Fluorescein Methotrexate, Triammonium Salt, 1 mg

00023-1 EA
EUR 285

Staurosporine

00025 100uG
EUR 100
Description: N/A

Staurosporine

00025-1 EA
EUR 100

Alpha-Bungarotoxin, CF®543, 500 ug

00026 500uG
EUR 527
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®543, 500 ug

00026-1 EA
EUR 527

Alpha-Bungarotoxin, CF®543, 100 ug

00026-100ug 1UG
EUR 132
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Rhodamine Phalloidin 300U

00027 300
EUR 364
Description: N/A

Rhodamine Phalloidin 300U

00027-1 EA
EUR 364

Biotin-XX-Phalloidin

00028 100U
EUR 466
Description: N/A

Biotin-XX-Phalloidin

00028-1 EA
EUR 466

Fluorescein-Phalloidin

00030 300U
EUR 364
Description: N/A

Fluorescein-Phalloidin

00030-1 EA
EUR 364

Rhodamine 110 Phalloidin

00032 300ST
EUR 364
Description: N/A

Rhodamine 110 Phalloidin

00032-1 EA
EUR 364

Sulforhodamine 101 (Texas Red®) Phalloidin

00033 300EU
EUR 364
Description: N/A

Sulforhodamine 101 (Texas Red®) Phalloidin

00033-1 EA
EUR 364

Phalloidin, CF®405M

00034 300U
EUR 482
Description: N/A

Phalloidin, CF®405M

00034-1 EA
EUR 482

Phalloidin, CF®405M

00034-T 50U
EUR 101
Description: N/A

Phalloidin, CF®405M

00034-T-1 EA
EUR 101

CF®488A-cAMP

00036 100ug
EUR 136
Description: N/A

CF®488A-cAMP

00036-1 EA
EUR 136

CF®640R-cAMP

00037 100ug
EUR 136
Description: N/A

CF®640R-cAMP

00037-1 EA
EUR 136

Phalloidin, CF555

00040 300U
EUR 530.4
Description: Minimum order quantity: 1 unit of 300U

Phalloidin, CF555

00040-T 50U
EUR 159.6
Description: Minimum order quantity: 1 unit of 50U

Phalloidin, CF®647, 300 U

00041 300U
EUR 482
Description: N/A

Phalloidin, CF®647, 300 U

00041-1 EA
EUR 482

Phalloidin, CF®647, 50 U

00041-T 50U
EUR 101
Description: N/A

Phalloidin, CF®647, 50 U

00041-T-1 EA
EUR 101

Phalloidin, CF®488A, 300 U

00042 300U
EUR 482
Description: N/A

Phalloidin, CF®488A, 300 U

00042-1 EA
EUR 482

Phalloidin, CF®488A, 50 U

00042-T 50U
EUR 101
Description: N/A

In current years, novel research have emerged, combining NK cells with different immunotherapeutic brokers, reminiscent of monoclonal antibodies, which could enhance scientific efficacy. Moreover, genetically-modified NK cells aimed toward arming NK cells with higher efficacy and persistence have appeared as another choice. Here, we evaluate novel pre-clinical and scientific research printed within the final 5 years administering NK cells as a monotherapy and mixed with different brokers, and we additionally evaluate chimeric antigen receptor-modified NK cells for the therapy of most cancers sufferers.